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What is Quetiapine (Seroquel®)?

Quetiapine, commonly known as Seroquel®, is an atypical antipsychotic medication primarily used to treat schizophrenia and bipolar disorder. It works by regulating the levels of dopamine and serotonin, two chemicals in the brain that regulate mood, behavior, and thought processes. While it is primarily used to treat depression and anxiety disorders, Seroquel for sleep has been explored for treating sleep disorders.

What are Quetiapine's Side Effects?

As with any medication, quetiapine can cause side effects, which vary depending on the individual's age, health condition, and dosage. Some common side effects include:

  • Drowsiness and fatigue

  • Headache

  • Dizziness

  • Dry mouth

  • Weight gain

  • Constipation

  • Increased appetite

  • Upset stomach

  • Blurred vision

  • Decreased blood pressure

  • Increased heart rate

  • Restlessness

  • Tremors

Other more severe side effects that require immediate medical attention include:

  • Allergic reactions, such as hives, itching, swelling, and difficulty breathing

  • Suicidal thoughts or behavior

  • Seizures

  • High fever

  • Trouble swallowing

  • Yellowing of the skin or eyes

  • Uncontrollable muscle movements

Patients taking quetiapine should be closely monitored for signs of these side effects, particularly in the first few weeks of treatment. It's also important to tell your doctor about any other medications, supplements, or herbal remedies you are taking, as some may interact with quetiapine.

How is Quetiapine (Seroquel®) Prescribed?

Quetiapine is usually prescribed by a psychiatrist or a primary care physician who specializes in mental health. The dosage and duration of treatment depend on the patient's medical history, current health status, and response to the medication. The medication is available in tablet form, and the dosage can be adjusted according to the patient's needs.

It's important to take quetiapine exactly as prescribed, at the same time every day, with or without food. Patients shouldn't stop taking the medication suddenly without consulting their doctor, as this can cause withdrawal symptoms.

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What are the alternatives to Quetiapine (Seroquel®)?

There are several alternatives to quetiapine (Seroquel) for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. These alternatives may include other antipsychotic medications, mood stabilizers, and antidepressants. It's important to note, however, that each individual's treatment needs are unique, and what works well for one person may not work as well for another. Therefore, it's important to work closely with your healthcare provider to determine the most appropriate treatment plan for your specific needs. Some alternatives include:

See if Your Prescriptions Qualify for Cabinet®!

See if your prescriptions qualify, and start loving your pharmacy. Search for one of your prescriptions below to find out whether you can transfer to Cabinet® for: A free personalized, refillable-for-life glass bottle (no more orange plastic!), a medicine travel carrier, plus a bottle of 24 Hr Allergy Relief (Zyrtec®) free. If eligible, our pharmacists handle an easy transfer from your current pharmacy, & refills are handled for you with your prescriber!


These medications work by regulating the levels of dopamine and serotonin in the brain, similar to quetiapine. However, they may have different side effects and dosage requirements, so it's important to consult with your doctor to determine the best treatment option for your condition.