Pain Reliever & Sleep Aid


Compare to Tylenol® PM

120 caplets
Relieves your minor aches and pains, while helping you fall asleep quickly for a good night's rest.
PainSleep Difficulty

Free carbon neutral shipping ($50+)

Refillable for life

FDA certified ingredients

Independently quality tested


  • Acetaminophen 500 mg (Pain reliever/fever reducer)
  • Diphenhydramine 25mg (Nighttime Sleep Aid)
  • One bottle, refillable for life. Shatter-tested and child safe, Cabinet’s stackable Pain Reliever & Sleep Aid bottle now comes prefilled with 120 caplets.

  • Ultimate peace of mind. Each batch of our medicines are quality tested by an independent lab, free of carcinogens and harmful additives, ensuring the highest possible quality.

  • Happier planet for generations to come. Ditching single-use plastic medicine bottles saves up to 1 lb of plastic annually from entering our oceans, landfills and air supply.

High quality & 
batch-level tested 
High quality & 
batch-level tested 
Sustainably produced & packaged
Sustainably produced & packaged
Space-saving & refillable bottles
Space-saving & refillable bottles
Compostable & commitment-free refills
Compostable & commitment-free refills

Meet the only


medicine system

PainFever PainSleep POUCH
Verified Medicines
Verified Medicines
A third party, independent lab tests all of our medicines to ensure you’re getting the highest quality active ingredients without any harmful filler.
The Future is Refillable
The Future is Refillable
We’re on a mission to eliminate single-use plastic from medicine with our refillable bottles and compostable refill pouches.*

Have questions?


Cabinet pouches are made out of 100% earth digestible materials (compostable materials). Specifically, the pouches are actually made out of wood cellulose and biomaterials. The pouch is compostable in city compost piles and is in the process of being BPI certified.

You can buy our refillable bottles! Here is a link to where you can find them.

The caps are made out of plastic. We are currently exploring using a plant-based plastic for these so that they can be recycled.

Cabinet pouches are made from wood cellulose and other biomaterials, all of which are 100% earth digestible. The pouches are municipal and industrial compostable (ASTM D6400). We are also currently testing the pouches for backyard compostability.


Cabinet Tension Headache Relief, a generic alternative to Excedrin® Tension Headache, is popular over-the-counter (OTC) combination pill used for headache relief. Each tablet contains two medicines, each working to relieve specific symptoms. How each individual ingredient works is explained below:

Acetaminophen: The active ingredient, acetaminophen, belongs to a group of medications called analgesics (pain relievers) and antipyretics (fever reducers). The exact way acetaminophen works in the body is not well known. It may work by decreasing the production of chemicals that cause inflammation, known as prostaglandins. It is also thought that acetaminophen can increase the pain threshold, making it so that more pain would have to develop for before you can feel it. Lastly, acetaminophen can act on the heat-regulating center of the brain (hypothalamus). When your temperature is high, it can tell this center of the brain to cool the body to bring your fever down. This ingredient is available separately as Cabinet Pain Reliever & Fever Reducer.

Caffeine: Caffeine works to relieve pain in an interesting way. The same way caffeine can be effective for pain relief is the same way caffeine can cause pain. When blood vessels expand or swell in the head, there is increased blood flow and pressure around the brain. This triggers nerves to send pain messages to the brain, which in turn produces feelings of a headache. Caffeine can step in to decrease swelling of blood vessels and stop blood from flowing to the brain. When caffeine is combined with a pain medication, such as acetaminophen, it can enhance the overall effect of the medication and help provide quicker pain relief.

Fun Fact! You may notice that when you drink a lot of coffee everyday, you get headaches when you stop drinking it. This is because the body can become dependent on caffeine. Regular caffeine consumption can cause regular narrowing of blood vessels around the brain, but what happens when you suddenly stop consuming caffeine? This lack of caffeine can cause an increase in blood flow and pressure around the brain that you are not used to. This is called a withdrawal headache. It can take a couple weeks for your body to adjust to not having caffeine regularly, so this is why it may be tough for someone to cut down on drinking coffee.

We know how important it is to know what you're putting inside your body. Please visit this link for a PDF of full drug facts for Cabinet Tension Headache Relief.

Avoid using Cabinet Tension Headache Relief with any other over-the-counter or prescription pain medicines that contain acetaminophen. Taking too much acetaminophen can cause liver injury. If you are not sure if a medicine has acetaminophen in it, check with a doctor or pharmacist. Some Cabinet medicines that have acetaminophen include: Daytime Severe Cold & Flu, Pain Reliever & Fever Reducer, and Pain Reliever & Sleep Aid. Do not use Cabinet Tension Headache Relief if you have ever had an allergic reaction to any ingredient in this product.

FAQs and Drug Facts Medically Reviewed by Joanna Tam, Healthcare and Content Manager

The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional. Consult your healthcare provider before starting or discontinuing any course of treatment.

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16 Reviews
  • Melissa E.
    Works as expected

    I love this product - much better than the name brand. I love the bottles and being able to know at a glance which medicine is which. I think the pain relief and sleep aid work seamlessly together for me.

  • Helen C.
    Constant pain

    I am in constant pain and have severe allergies to NSAIDs and prescription pain meds. Taking this Acetaminophen based sleep aid I am able to get a better nights sleep, then I take the Acetaminophen without sleep to help during the day. Both are extremely helpful as I am unable to stand up after sitting due to severe degenerative knee, hip, and lower back disease.

  • Kyra B.
    I have recently had knee

    I have recently had knee pain so bad it wakes me at night, but this helps me sleep through the night again.

  • Susan H.
    Great as a sleep aid, not so great as a pain reliever. I took it just before I went to bed and, within minutes, I could feel it putting me to sleep. Slept through the night. I have chronic pain, so perhaps it did work as a pain reliever allowing me to sleep through the night. I love the idea of a refillable bottle. Will order again!


  • Sarah T.
    we love the simplicity of

    we love the simplicity of everything cabinet offers from the ordering process to the shipping and packaging to how they look on my shelf!