Amitriptyline (generic for Elavil®)

FDA Approved

Have a prescription? Get your amitriptyline refills in sustainable packaging with Cabinet Health.
DepressionNerve Pain
  • Amitriptyline Hydrochloride

Generic For Elavil®

Medication Strengths:
Day Supply:
Save $6 + 2 shipments with 90 day supply
How Many Do You Take A Day?
Total Count: 30 tablets
To see your bottle rendered, type your full name:
Hi! Want to see what your personalized bottle would look like?
30 day money-back guarantee | Free shipping over $45

How does Cabinet care for you?

  1. Seamless transfer process. Our pharmacist will coordinate with your current pharmacy or provider to transfer your prescription.

  2. Better for the planet. Our pharmacy will send your prescription refills in plastic-free, compostable pouches.

  3. Stress-free refills. Our care team will help manage your refills and prescription renewals, so you don't have to worry about running out of pills.

  4. Satisfaction guarantee. If your care needs aren't being met, our care team is here and eager to help! If you're not satisfied, we can transfer your prescription back to your old pharmacy at any time.

Doctor illustration - prescription

Have a specific

Speak with a Pharmacist

Meet the only sustainable

medicine system

CAB-10027-Pain-Reliever- -Fever-Reducer-Acet-action-centered-sRGB-system-visualized-mobile-q=90-label
Compostable Refills
Compostable Refills
Eliminate excessive plastic waste with each refill and compost the packaging!
A Sustainable Pharmacy
A Sustainable Pharmacy
We created a pharmacy focused on reducing plastic and medical waste
Transforming the medicine industry!
A new way of buying medications
Sustainable and elevated

Frequently Asked Questions

About the Drug

Amitriptyline is the generic equivalent of Elavil®, Amitril®, Amitid®, and Endep®.

By law, a generic drug must be the same as its brand name counterpart in terms of active ingredient, dosage, safety, effectiveness, strength, stability, and quality. A generic may, however, differ in its inactive ingredients (i.e. flavoring, fillers, and preservatives).

Amitriptyline is FDA approved for the treatment of:

  • Major depressive disorder (MDD) or depression

Amitriptyline may be used off-label for:

  • Migraine prevention

  • Postherpetic neuralgia

  • Nerve pain

  • Eating disorders

  • Fibromyalgia

Amitriptyline is a tricyclic antidepressant (TCA). It works by blocking the brain’s absorption of norepinephrine and serotonin, “feed good” chemicals in your brain. The end result? An increased level of norepinephrine and serotonin in your brain, which is thought to improve mood.

The most common side effects of amitriptyline include:

  • Dry mouth

  • Constipation

  • Nausea/vomiting

  • Blurred vision, lightheadedness

  • Low or high blood pressure

  • Allergic reaction (i.e. skin rash, swelling of the face and tongue, itching, trouble breathing)

  • Drowsiness

  • Altered sex drive

  • Numbness or tingling in the hands and feet

  • Weight gain or loss

  • Withdrawal symptoms—abrupt discontinuation of treatment can cause nausea, headache, and general discomfort

  • Changes in blood sugar levels

Side effects may improve over time as your body adjusts to the medicine.

This list doesn’t represent all possible side effects (or serious side effects) of amitriptyline. If you’re experiencing any ongoing, bothersome side effect(s), tell your healthcare provider right away.

If you’d like to learn more, speak with your doctor or pharmacist. The Food and Drug Administration (FDA) also has a helpful medication guide for amitriptyline here.

Amitriptyline (Elavil®) does come with serious warnings. These include:

  • Increased risk of suicidal thoughts or actions in adolescents and young adults*

  • Serotonin syndrome—a rare, but potentially life-threatening condition that occurs when there’s too much serotonin in the brain

  • Manic episodes or hypomania in patients with bipolar disorder

  • Increased risk of irregular heartbeat or heart attack in people with a history of heart disease

  • Seizures

  • Glaucoma

If any of the above concern you, speak with your doctor or pharmacist about your perceived risk and other treatment options that exist.

*This warning is a boxed warning. A boxed warning is the most serious type of medication warning assigned by the FDA.

Frequently Asked Questions

Amitriptyline may be taken with or without food.

If you accidentally miss your dose of amitriptyline, take the dose as soon as you remember. If it’s almost time for your next dose (within 2 hours), skip the missed dose and take your next dose at the usual time. Don't take 2 doses at the same time or extra doses.

During pregnancy: The safety of amitriptyline use during pregnancy hasn’t been established and results from animal reproduction studies remain inconclusive.

While breastfeeding: Amitriptyline can pass into breastmilk and may cause side effects in your infant.

It’s important to treat mental health-related conditions when pregnant or nursing, as untreated depression, anxiety, or other mental illnesses can harm both you and baby. Always let your healthcare professional know if you’re pregnant or breastfeeding, so you can discuss the benefits and risks of starting or continuing amitriptyline.

It’s recommended to avoid or limit the use of alcohol when taking amitriptyline. Alcohol can intensify the side effects of amitriptyline, including dizziness and sleepiness.

Amitriptyline can interact with some prescription drugs and supplements. It’s always recommended to give both your doctor and pharmacy an updated list of everything you’re taking, so drug interactions can be identified.

Some medicines and supplements amitriptyline can interact with include:

  • Topiramate

  • Reserpine

  • Cimetidine

  • Opioids: tramadol, fentanyl

  • SSRIs (selective serotonin reuptake inhibitors): citalopram, sertraline, fluoxetine, paroxetine

  • Monoamine oxidase inhibitors (MAOIs): selegiline, phenelzine, linezolid, methylene blue, tranylcypromine, isocarboxazid

  • SNRIs (serotonin and norepinephrine reuptake inhibitors): desvenlafaxine, venlafaxine, duloxetine, milnacipran

  • Triptans: sumatriptan, eletriptan, naratriptan

  • St. John’s Wort

  • Amitriptyline

  • Epinephrine

  • Thyroid medications

This list doesn’t represent all the drugs that may not be safe to take with amitriptyline. If you’re unsure whether a certain drug or supplement can be taken with amitriptyline, speak with your doctor or pharmacist. The FDA also has a helpful medication guide for amitriptyline here.

FAQs and Drug Facts Medically Reviewed by Joanna Tam, Healthcare and Content Manager

Disclaimer: The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions, or adverse effects and is not a substitute for the expertise and judgment of your healthcare professional. Consult your healthcare provider before starting or discontinuing any course of treatment.

On The Blog

Sustainable Healthcare Stamp