Duloxetine (generic for Cymbalta®)

FDA Approved

$16.66
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  • Duloxetine Hydrochloride

Generic For Cymbalta®

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How does Cabinet care for you?

  1. Seamless transfer process. Our pharmacist will coordinate with your current pharmacy or provider to transfer your prescription.

  2. Better for the planet. Our pharmacy will send your prescription refills in plastic-free, compostable pouches.

  3. Stress-free refills. Our care team will help manage your refills and prescription renewals, so you don't have to worry about running out of pills.

  4. Satisfaction guarantee. If your care needs aren't being met, our care team is here and eager to help! If you're not satisfied, we can transfer your prescription back to your old pharmacy at any time.

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Frequently Asked Questions

Frequently Asked Questions

Duloxetine can interact with some prescription medication and supplements. It’s always recommended to give both your doctor and pharmacy an updated list of everything you’re taking, so drug interactions can be identified.

Some medicines and supplements duloxetine can interact with include:

  • SSRIs (selective serotonin reuptake inhibitors): citalopram, sertraline, fluoxetine, paroxetine

  • Monoamine oxidase inhibitors (MAOIs): selegiline, phenelzine, linezolid, methylene blue, tranylcypromine, isocarboxazid

  • SNRIs (serotonin and norepinephrine reuptake inhibitors): desvenlafaxine, venlafaxine, milnacipran

  • Triptans: sumatriptan, eletriptan, naratriptan

  • Arrhythmia medications: propafenone, flecainide

  • Alcohol

  • NSAIDs: aspirin, ibuprofen

  • Warfarin

  • Tramadol

  • Cimetidine

  • St. John’s Wort

  • Ciprofloxacin

This list doesn’t represent all the drugs that may not be safe to take with duloxetine. If you’re unsure whether a certain drug or supplement can be taken with duloxetine, seek medical advice from your doctor or pharmacist. The FDA also has a helpful medication guide for duloxetine here.

If you accidentally miss your dose of Duloxetine, take the dose as soon as you remember. If it’s almost time for your next dose (within 2 hours), skip the missed dose and take your next dose at the usual time. Don't take 2 doses at the same time or extra doses.

Duloxetine may be taken with or without food. Take each capsule whole. Avoid crushing, chewing, or opening the capsule.

During pregnancy: The safety of Duloxetine use during pregnancy isn’t well established.

While breastfeeding: The safety of Duloxetine in infants is unknown. Use of this drug while nursing isn’t recommended.

It’s important to treat mental health-related conditions when pregnant or nursing, as untreated depression, anxiety, or other mental illnesses can harm both you and baby. Always let your provider know if you’re pregnant or breastfeeding, so you can discuss the risks and benefits of taking Cymbalta (Duloxetine).

It’s recommended to avoid or limit the use of alcohol when taking Duloxetine. Liver failure has been reported in patients taking duloxetine and the risk is much higher for patients with substantial alcohol use.

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FAQs and Drug Facts Medically Reviewed by Joanna Tam, Lead Pharmacist | PharmD

Disclaimer: The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions, or adverse effects and is not a substitute for the expertise and judgment of your healthcare professional. Consult your healthcare provider before starting or discontinuing any course of treatment.

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