Risperidone (generic for Risperdal®)
FDA Approved
Risperidone (generic for Risperdal®)
- Risperidone ()
Generic For Risperdal®
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Frequently Asked Questions
Risperidone is the generic equivalent of Risperdal®.
By law, a generic drug must be the same as its brand name counterpart in terms of active ingredient, dosage, safety, effectiveness, strength, stability, and quality. A generic may, however, differ in its inactive ingredients (i.e. flavoring, fillers, and preservatives).
Risperidone is FDA approved for the treatment of:
Schizophrenia
Acute manic or mixed episodes associated with Bipolar I Disorder (taken alone, or in combination with lithium or valproate)
Irritability associated with autistic disorder
Risperidone (Risperdal®) does come with serious warnings. These include:
Increased risk of death and cerebrovascular events (i.e. stroke, transient ischemic attack) in older adults with dementia-related psychosis*
Neuroleptic Malignant Syndrome
Tardive dyskinesia—a movement disorder featuring uncontrollable, strange, repetitive movements of the face and/or other body parts
Metabolic changes, including high blood sugar, increased cholesterol and triglycerides, and weight gain
Elevated prolactin levels (hyperprolactinemia)
Increased fall risk
Infection risk due to decreased white blood cell count (WBC)
Cognitive and motor impairment
Seizures
If any of the above concern you, speak with your doctor or pharmacist about your perceived risk and other treatment options that exist.
*This warning is a boxed warning. A boxed warning is the most serious type of medication warning assigned by the FDA.
Risperidone is an atypical antipsychotic. How risperidone works remains unclear, but it’s thought to work on certain neurotransmitters (dopamine and serotonin) in the brain to improve behaviors and mood.
The most common side effects of risperidone include:
Slowed movements, rigidity, and tremors (Parkinsonism)
Restlessness (akathisia)
Shaking or tremor
Dizziness, drowsiness
Dry mouth
Anxiety
Blurred vision
Nausea/vomiting
Upper abdominal pain, stomach discomfort
Diarrhea, constipation
Upper respiratory tract infection
Side effects may improve over time as your body adjusts to the medicine.
This list doesn’t represent all possible side effects (or serious side effects) of risperidone. If you’re experiencing any ongoing, bothersome side effect(s), tell your healthcare provider right away.
If you’d like to learn more, speak with your doctor or pharmacist. The Food and Drug Administration (FDA) also has a helpful medication guide for risperidone here.
Risperidone can interact with some medicines and supplements. It’s always recommended to give both your doctor and pharmacy an updated list of everything you’re taking, so drug interactions can be identified.
Some medicines and supplements risperidone can interact with include:
Drugs that act on the central nervous system (CNS): carbamazepine, lithium, valproate
Antidepressants: sertraline, citalopram, fluoxetine, fluvoxamine, nefazodone, paroxetine, amitriptyline, mirtazapine
Certain anti-infective drugs: erythromycin, fluconazole, indinavir, ketoconazole, posaconazole, ritonavir
Cimetidine
Digoxin
Clozapine
Ondansetron
St. John’s Wort
Thioridazine
Pimozide
Alcohol
Benzodiazepines: lorazepam, diazepam
This list doesn’t represent all the drugs that may not be safe to take with risperidone. If you’re unsure whether a certain drug or supplement can be taken with risperidone, speak with your doctor or pharmacist. The FDA also has a helpful medication guide for risperidone here.
If you accidentally miss your dose of risperidone, take the dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and take your next dose at the usual time. Don't take 2 doses at the same time or extra doses.
Risperidone may be taken with or without food.
During pregnancy: Limited data exists on the effects of risperidone-use during pregnancy. According to some data, newborns exposed to antipsychotic drugs during the 3rd trimester of pregnancy may be at risk for experiencing withdrawal following delivery.
While breastfeeding: Limited data exists on the effects of risperidone on lactation. There have been reports of sedation, failure to thrive, and tremors in breastfed infants exposed to risperidone.
It’s important to treat mental health-related conditions when pregnant or nursing, as untreated depression, anxiety, or other mental illnesses can harm both you and baby. Always let your provider know if you’re pregnant or breastfeeding, so you can discuss the risks and benefits of starting or continuing risperidone.
It’s recommended to avoid or limit the use of alcohol when taking Risperidone. Alcohol can intensify the side effects of risperidone, including dizziness and sleepiness.
by Medical Writing Team, Supported by PharmDs
Disclaimer: The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions, or adverse effects and is not a substitute for the expertise and judgment of your healthcare professional. Consult your healthcare provider before starting or discontinuing any course of treatment.
